A critical step in applying a computational approach for drug discovery under the new outbreak situation

Thanet Pitakbut (TP) *, Sukanya Dej-adisai (SD) * / 2020-12-31

The urgency of the drug discovery against viral infection is raising after the emergence of 2019 new coronavirus epidemic in China. The traditional drug discovery requires years of operation. Therefore, the fast-track strategy has been proceeded by applying a computer-based approach. However, the…

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Anti-cancer property from a Thai medicinal plant

Sarayut Radapong (SR) *, Satyajit D. Sarker, Kenneth J. Ritchie (KJR) * / 2020-12-31

Oxyresveratrol poses potent cytotoxicity to several kinds of cancer cells. The compound moderated various molecular alterations of breast cancer cells including apoptosis, cell proliferation, metastasis and cancer repair pathways. Interestingly, Oxyresveratrol down-regulates RAD51 and genes in…

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Atmospheric Water Generator

Harit Keawmuang * / 2020-12-31

There are still many places in the world where safe drinkable water is not available. The reason mostly lies in not having enough freshwater resources and the cleanliness of the water. In order to solve these problems, an atmospheric water generator serves to produce clean potable water by using the…

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Automatic Brain Tumour Regions Segmentation Using Modified U-Net

Keerati Kaewrak *, John Soraghan, Gaetano Di-Caterina, Derek Grose / 2020-12-31

Early diagnosis is an important key for brain tumour patients' survival. The segmentation of the tumour regions is done manually by the experts and it is time-consuming. In this work, we present a novel network architecture that automatically segments the whole tumour regions and intra-tumour…

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Cooperativity in non-covalent metallophilic Pt···Pt interaction of aggregated square-planar Pt(II) complexes bearing isoquinolinyl pyrazolate; Theoretical insights

Chattarika Sukpattanacharoen, Prashant Kumar, Nawee Kungwan (NK) *, Daniel Escudero (DE) * / 2020-12-31

Pt···Pt contacts are more evident in the trimer aggregates rather than in the dimer ones, and especially in the case of the T1 optimized geometries. Esyn and E-EA values indicate a positive synergy between both interactions which is in good agreement with the shortening of the equilibrium distance…

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Effects of Macro Uncertainty on Subjective Uncertainty and Mean Expectation

Giulia Piccillo (GP) *, Poramapa Poonpakdee (PP) * / 2020-12-31

Macro uncertainty affects the assessed probabilistic distribution of individual economic forecasts. In this study, we empirically document the effects of macro uncertainty on subjective uncertainty (second moment) and mean expectation (first moment) of GDP growth and income forecasts. Based on the…

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Identification of volatile organic compounds by use of Field Asymmetric Ion Mobility Spectrometry

Nattapong Chantipmanee *, Peter C. Hauser / 2020-12-31

Field Asymmetric Ion Mobility Spectrometer (FAIMS) provides rapid (30 seconds for a sample) analysis under atmospheric pressure. […] * corresponding author (chantipmanee.n@hotmail.com) Received: 28 February 2020, Accepted: 06 June 2020, Published: 31 December 2020 DOI: 10.5281/zenodo.4383331…

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Image Inpainting with Variational Autoencoders

Sanhanat Deesamutara *, Federico Maggiore / 2020-12-31

This work presents the training methodology of variational autoencoder in order to restore the missing part of a corrupted image and question the requirement of homogeneity in the implementation and difference situation of corrupted data. […] * corresponding author…

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Investigating a challenge of building a superconducting quantum computer

Nuttamas Tubsrinuan *, Gustav Andersson, Per Delsing / 2020-12-31

Parasitic two-level systems (TLS) coupling to a superconducting quantum circuit causes information loss. To mitigate this problem, a better physical understanding of the coupling mechanism is crucial. Phase noise caused by TLS interaction is investigated by using a surface acoustic wave resonator.…

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Lessons learnt from Impact to World’s Aviation due to Covid-19

Tanut Ungwattanapanit / 2020-12-31

The world’s aviation industry had been skyrocketing for the past decades. The demand for new aircraft was so high that airlines complained to Airbus for failing to deliver aircraft on time. Suddenly right after Chinese New Year this year, the world of aviation has collapsed nearly completely.…

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Protein extraction from Rice bran

Suriphon Siwongsa * / 2020-12-31

Rice bran is a by-product of the rice milling process, which is classified as a waste. However, there has been research done earlier; found that rice bran contains a massive number of proteins when compared to other plants. The extraction of plant proteins using cellulase enzymes is considered…

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Regulating Online Defamatory and Insulting Speech under Thai Law

Cheewin Mallikamarl * / 2020-12-31

The Internet allows us to freely express ideas more than other types of communication. Some online speech may impact a personality right. Law should strike a fair balance between preserving the freedom of speech and providing the protection to a personality right. Thai law protects personality…

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Risk assessment of a self-tracking EM-integrated fetoscope

Wipharat Phokee *, Mirza Awais Ahmad, Jan Deprest, Emmanuel Vander Poorten, Liliane Pintelon / 2020-12-31

Embedding an electromagnetic (EM) sensing at the tip of a fetoscope is appealing as it would allow to record the position and orientation of the tip of the fetoscope in real time. This tracking information may be useful for advanced guidance schemes that may help the surgeon during the intervention.…

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The residential site environmental preferences of older adults in a rural Asian context from a case study of a village in Northern Thailand

Alisa Hongthong *, Patricia Noxolo, Lloyd Jenkins, Yueming Zhang / 2020-12-31

This study examines elders’ preferences for residential site environments from their perceptions and evaluations. Unlike most earlier works on environments for elders, the study focuses on residential sites in a rural Asian context, with a mixed-methodology based on the extent of Person-Environment…

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Xanthine Oxidoreductase Mediates Nitrite-Induced Platelet Inhibition

Tipparat Parakaw, Rayomand Khambata, Amrita Ahluwalia * / 2020-12-31

Xanthine oxidoreductase (XOR) is a potential missing link in platelet hyperactivity and cardiovascular diseases. Bioconversion of NO2- to NO by XOR modulates platelet reactivity as we observed rises in plasma NO2- levels after Xdh allele deletion in mice. This higher plasma NO2- in Xdh heterozygous…